KMID : 0978920200210020094
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Korean Journal of Clinical Geriatrics 2020 Volume.21 No. 2 p.94 ~ p.102
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Associations among Coronary Artery Calcium Score, Left Ventricular Mass Index and Septal E/E¡¯ Ratio in Subjects with Normal Left Ventricular Ejection Fraction
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Jeon Ung
Park Sang-Ho
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Abstract
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Background: The objective of this study is to determine if associations among the coronary artery calcium (CAC) score (CACS), left ventricular mass index (LVMI), and septal E/E¡¯ ratio.
Methods: We investigated 1230 consecutive subjects with a normal left ventricular ejection fraction who underwent multidetector computed tomography and echocardiography. The CACS was measured using the Agatstone method. Participants were classified as follows, in a two-fold manner: first, negative CAC (CACS=0) group and positive CAC (CACS £¾0) group; second, no (CACS=0), mild (1-100), moderate (101-400), and severe CAC deposits (£¾400).
Results: In multivariate binary logistic regression adjusted for covariates, the LVMI and septal E/E¡¯ ratio were independent predictors of positive CAC deposits (CACS £¾0) and severe CACS (CACS £¾400). Regarding the ¡°composite score¡± based on a septal E/E¡¯ ratio ¡Ã15 and LVMI ¡Ã90 g/m2, a higher score was associated with a greater CACS. Per the severity criteria of the CACS, severe CAC deposits were significantly associated with ¡°composite score 2¡± group and the odds ratios in each group were 1.790, 2.126, and 5.705, respectively.
Conclusion: In our study, the LVMI and septal E/E¡¯ ratio were associated with the CACS, independent of classic risk factors in patients with chest pain or without symptoms with a normal left ventricular ejection fraction.
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KEYWORD
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Calcium, Coronary, Echocardiography, Multidetector computed tomography
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